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C-reactive protein (CRP) by nephelometry

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of C-reactive protein, a protein produced by your liver in response to inflammation or infection.

Quick summary

["CRP helps track inflammation in your body."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
37838-0
Short code
Deprecated Wrist-R XR 4V
Synonyms
Deprecated Wrist-R XR 4V
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
xr
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order a CRP test to check for signs of inflammation, monitor conditions like arthritis, heart disease, or infections, or evaluate responses to treatments. It can also help assess risk for certain diseases or conditions, such as cardiovascular disease.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for 8–12 hours before the test if your blood is drawn from a vein, but this is not always required. If you’re taking blood from a fingerstick (e.g., for a finger-prick test), fasting may not be necessary.

What Happens During the Test?

A healthcare professional will draw blood from a vein in your arm or, if needed, from a finger. The blood sample is then sent to a lab where it is analyzed using nephelometry, a method that measures how much light scatters from CRP particles in your serum.

What Do the Results Mean?

Results are reported in milligrams per liter (mg/L). Higher levels may indicate inflammation, infection, or other health issues, while lower levels suggest minimal inflammation. Your results will be interpreted by your healthcare provider based on your overall health and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

CRP (Nephelometry)

Frequently asked questions

What causes CRP levels to be high?
CRP levels can rise due to infections (like colds or flu), injuries, surgeries, or certain medications. Chronic conditions such as arthritis, heart disease, or inflammatory bowel disease may also lead to elevated CRP. Stress, smoking, or obesity can sometimes contribute as well.
What does a high CRP level mean?
A high CRP level suggests inflammation is present in your body. Your doctor will use these results along with other tests and symptoms to determine the cause and next steps, such as starting treatment for an infection, managing an autoimmune condition, or assessing cardiovascular risk.
Can CRP levels be affected by diet or lifestyle?
Yes, lifestyle factors like diet, exercise, smoking, and weight can influence CRP levels. Eating a heart-healthy diet, staying physically active, and avoiding smoking may help lower CRP and reduce inflammation over time.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy