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Multisectional Sagittal Serum Protein Electrophoresis (Qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the distribution of different protein fractions in your blood serum using electrophoresis, a technique that separates proteins based on size and charge.

Quick summary

["Helps identify abnormal protein patterns that may signal conditions like infections, inflammation, or inherited disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
25051-4
Short code
Deprecated XXX CT Multisectional sagitta
Synonyms
Deprecated XXX CT Multisectional sagitta
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ct
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

Electrophoresis divides blood proteins into distinct bands (fractions) based on their electrical charge and molecular weight. Key fractions include albumin, alpha-globulins, beta-globulins, and gamma-globulins. Abnormal band patterns can indicate conditions affecting protein production or function.

Common Clinical Uses

This test is often used to diagnose or monitor conditions such as multiple myeloma, Waldenström macroglobulinemia, chronic inflammatory diseases, or certain genetic disorders like alpha-1 antitrypsin deficiency. It may also help assess protein loss in kidney disease or liver dysfunction.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in the arm. The serum (liquid part after clotting) is then separated and analyzed in a lab to create the protein profile.

Interpretation and Results

Results are presented as a graphical profile showing the relative amounts of each protein fraction. A healthcare provider will compare these results to your clinical picture and reference ranges to determine if further testing or treatment is needed.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Abnormal protein patterns can signal underlying health issues. For example, elevated gamma-globulins may suggest chronic infection or autoimmune disease, while unusual band shifts could indicate inherited metabolic disorders or malignancies. Always discuss results with your doctor.

Short name

Multisectional Serum Protein Electrophoresis (Qualitative)

Frequently asked questions

Why might I need this test?
Your doctor may recommend this test if you have symptoms like unexplained weight loss, fatigue, swelling, or if they suspect a condition affecting protein levels in your blood.
What does a normal result mean?
A normal result shows balanced protein fractions, but this doesn’t rule out all conditions. Your doctor will consider your overall health and other test results when interpreting results.
Can I prepare for this test?
No special preparation is needed. You may eat and drink normally before the test, but inform your doctor about any medications you’re taking, as some can affect protein levels.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy