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Total Protein in Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of protein in your blood serum, which includes albumin and globulins.

Quick summary

["Your blood protein levels help assess overall health and detect potential issues like malnutrition or kidney problems."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
109350-9
Short code
D farinae IgG Msmt Ser
Synonyms
D farinae IgG Msmt Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Total Protein Used For?

Total protein is a simple blood test that helps doctors evaluate your nutritional status, kidney function, and liver health. It can also be used to monitor conditions like chronic kidney disease or malnutrition. Low levels may suggest poor absorption of nutrients, while high levels could indicate dehydration or liver disease.

Why Might You Need This Test?

Your doctor may order this test if you have symptoms like unexplained weight loss, swelling, fatigue, or if they suspect conditions like liver disease, kidney problems, or malnutrition. It’s also sometimes checked during routine health assessments or before certain treatments.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if it’s part of a more complex blood workup. Wear comfortable clothing and plan to stay for about 15 minutes while the blood is drawn.

What Happens During the Test?

A healthcare provider will insert a small needle into a vein in your arm. You may feel a slight pinch, but it’s usually over quickly. The blood sample is then sent to a lab for analysis. The process takes a few minutes, and you can resume normal activities afterward.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total Protein

Frequently asked questions

How Does Total Protein Affect My Health?
What Are Common Causes of Abnormal Results?
How Often Should I Get This Test?
Can I Prepare for This Test at Home?
What If I Have a Fear of Blood Draws?
Many people feel nervous about blood tests. You can ask your healthcare provider about numbing cream or distraction techniques. If possible, bring a support person or use relaxation methods like deep breathing to help ease anxiety.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy