Total Protein with Albumin/Globulin Ratio (Serum)

What Does This Test Measure?

Total protein reflects the combined amount of albumin and globulin in your serum. Albumin is the primary protein that helps maintain fluid balance in your blood vessels, while globulins include proteins involved in immune function and transport of substances like hormones and metals. The ratio between these proteins can indicate underlying health conditions.

Why Is This Test Done?

Doctors may order this test to evaluate protein levels in cases of suspected malnutrition, kidney disease, liver problems, or chronic infections. It can also help monitor treatment responses for conditions affecting protein synthesis or loss.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for 8–12 hours before the draw if your blood is collected early in the morning. Wear a loose shirt for easy access to your arm.

What Happens During the Test

A healthcare provider will insert a small needle into a vein in your arm to collect a blood sample. You may feel a slight pinch, but the procedure usually takes just a few minutes. You can resume normal activities afterward.