24-Hour Urine Test for Dehydroepiandrosterone Sulfate (DHEAS) Mass Concentration

Why This Test Is Done

Your doctor may order this test if they suspect conditions affecting hormone production, such as adrenal gland issues, hormonal imbalances, or to monitor treatment for conditions like Cushing’s syndrome or adrenal insufficiency. It can also help evaluate symptoms like irregular periods, low libido, or signs of hormone-related disorders.

What to Expect Before the Test

No special preparation is needed. Collect all urine produced in a 24-hour period (typically from one morning to the next morning) in a clean container. Drink plenty of water to help flush out hormones naturally. Avoid certain medications or supplements that might affect hormone levels unless instructed otherwise.

What the Test Results Mean

Results are compared to general reference ranges for healthy adults, but individual values can vary widely. High levels might suggest overactive adrenal glands or other hormonal conditions, while very low levels could indicate adrenal insufficiency or other metabolic issues. Your doctor will interpret results in the context of your overall health and symptoms.

Common Conditions Monitored

This test is often used to diagnose or monitor conditions like adrenal tumors, congenital adrenal hyperplasia, or to evaluate hormonal imbalances in people with conditions such as polycystic ovary syndrome (PCOS) or androgen excess disorders.