Dehydroepiandrosterone sulfate (DHEAS) – Serum
This test measures the level of dehydroepiandrosterone sulfate (DHEAS), a hormone produced primarily in the adrenal glands. It reflects your body’s production of this steroid precursor, which can influence sex hormone balance.
["DHEAS helps assess adrenal function and may indicate hormonal health, especially in conditions affecting sex hormones."]
Key facts at a glance
- LOINC
- 31020-1
- Short code
- DHEA Amn-mCnc
- Synonyms
- DHEA Amn-mCnc
- Category
- chemistry
- Sample
- fluid
- Container
- Sterile tube
- Units
- N/A
- Ref low
- 135
- Ref high
- 980
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82626
- Specimen volume
- 2-5 mL
- Stability
- Room temperature: 2h, Refrigerated: 24h
- Hemolysis max
- 300
- TAT
- 4–24 hours
- Order
- routine
What Is DHEAS Used For?
DHEAS is often measured to evaluate adrenal gland health, particularly in cases of suspected adrenal insufficiency, hormonal imbalances, or conditions like Cushing’s syndrome or congenital adrenal hyperplasia. It can also be part of a broader evaluation for sex hormone-related disorders.
How Is the Test Performed?
A blood sample is drawn from a vein, usually in your arm. The blood is then sent to a lab for processing. The test measures the sulfate form of dehydroepiandrosterone (DHEA), which is stored in your blood serum.
Why Might You Need This Test?
Your healthcare provider may order a DHEAS test if you have symptoms like fatigue, low libido, irregular menstrual periods, or signs of hormonal imbalances. It can also be used in research or monitoring certain medical conditions.
What Are Possible Results?
Results are not provided with specific reference ranges, as they can vary by lab and individual factors. Your doctor will interpret the results in relation to your symptoms and medical history.
Reference range
NCBI: DHEA-S Male 135-980 µg/dL; Female 30-260 µg/dLN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
DHEAS levels can be useful in diagnosing or monitoring conditions affecting adrenal function, sex hormone production, or metabolic health. Low levels may suggest adrenal insufficiency or other endocrine disorders, while very high levels could indicate conditions like polycystic ovary syndrome (PCOS) or tumors affecting hormone production.
Short name
DHEAS
Frequently asked questions
What Does a Low DHEAS Level Mean?
What Does a High DHEAS Level Mean?
How Often Should I Get This Test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy