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###1: Dehydroepiandrosterone (DHEA), 24-hour urine, mass concentration

Published: August 9, 2026Updated: August 17, 2026

###3: This test measures the amount of DHEA, an adrenal hormone with androgenic activity, collected in urine over 24 hours. A 24-hour collection can help assess the body’s overall excretion of DHEA.

Quick summary

["###4: The result is most useful when interpreted with symptoms, medical history, and other hormone tests."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
57787-4
Short code
DHEA Pre Dex 24h Ur-mCnc
Synonyms
DHEA Pre Dex 24h Ur-mCnc
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
135
Ref high
980
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82626
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

###5: What this test measures

###6: DHEA is produced mainly by the adrenal glands. This test measures its concentration in a complete 24-hour urine collection, providing information about how much DHEA the body is releasing and excreting.

###7: How the urine is collected

###8: Urine is collected for a full 24 hours, usually beginning in the morning. The container and collection instructions should be followed exactly, and the total urine volume and collection period are recorded so the laboratory can calculate the result appropriately.

###9: Why the test may be ordered

###10: A 24-hour urine DHEA test may be used to evaluate androgen production or excretion in people with hormonal symptoms, irregular menstrual cycles, acne, increased body hair, or other concerns. It may also be used alongside other tests when evaluating adrenal or reproductive hormonal disorders.

###11: Understanding an abnormal result

###12: Results that are higher or lower than expected may reflect normal biological variation, changes in adrenal function, medication effects, or differences in urine collection. A clinician should interpret the result with related hormones, symptoms, and examination findings.

Reference range

NCBI: DHEA-S Male 135-980 µg/dL; Female 30-260 µg/dLN/A

Specimen: urine

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

###13: Clinical significance: DHEA is an adrenal androgen, and altered urinary excretion can occur with hormonal disorders, ovarian dysfunction, adrenal abnormalities, and certain medicines or supplements. Because DHEA changes with age and has substantial day-to-day variation, a single result should not be used to diagnose a condition without clinical correlation.

Short name

###2: 24-hour urine DHEA

Frequently asked questions

###14: Is this the same as a serum DHEA test?
###15: No. This test measures DHEA in a 24-hour urine collection, whereas a serum test measures DHEA in a blood sample drawn at one time. The two results are related but are not interchangeable.
###16: Why is a 24-hour collection needed?
###17: A 24-hour collection provides a more representative measure of how much DHEA is excreted over a full day than a single urine sample. It also helps account for variable urine output when the laboratory evaluates the result.
###18: Can medications or supplements affect the result?
###19: Yes. Hormonal medicines, glucocorticoids, and DHEA-containing supplements can affect DHEA production or levels. Tell the healthcare professional about all medications, supplements, and hormone products before the collection.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy