Skip to content

Dehydroepiandrosterone (DHEA), 24-Hour Urine, Mass Concentration

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of dehydroepiandrosterone (DHEA) in urine collected for 24 hours. DHEA is an androgen produced mainly by the adrenal glands.

Quick summary

["The result can help assess adrenal androgen production when interpreted with symptoms, medical history, and other hormone tests."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
57783-3
Short code
DHEA pre hi Dex 24h Ur-mCnc
Synonyms
DHEA pre hi Dex 24h Ur-mCnc
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
135
Ref high
980
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82626
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The test measures DHEA, an adrenal androgen that contributes to the body's androgen levels. Urine testing can provide information about hormone production over the collection period.

How Is the Urine Collected?

Urine is collected for a full 24 hours, usually beginning after the first morning void is discarded. The container should be kept closed, refrigerated if instructed, and returned according to the laboratory's directions.

Why Is a 24-Hour Collection Used?

A 24-hour collection accounts for changes in urine output throughout the day. However, an incomplete collection, spilled urine, or an unusually short or long collection period can affect the result.

Factors That May Influence the Result

Adrenal disorders, ovarian dysfunction, pregnancy, puberty, and menopause can affect DHEA levels. Medications, supplements, stress, and the timing of the collection may also influence the result.

Reference range

NCBI: DHEA-S Male 135-980 µg/dL; Female 30-260 µg/dLN/A

Specimen: urine

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

DHEA measurements may be useful when evaluating unwanted androgen-related symptoms such as excess facial hair, acne, or menstrual irregularity, or when assessing adrenal function. The result should not be interpreted alone because DHEA varies with age, sex, hormone status, and collection completeness.

Short name

24-Hour Urine DHEA

Frequently asked questions

What does a high DHEA result mean?
A high result may indicate increased androgen production, but it can also reflect an adrenal or ovarian condition, normal individual variation, medications, or supplements. Your clinician will interpret it alongside your symptoms and other tests.
What does a low DHEA result mean?
A low result may occur with normal aging, reduced adrenal function, certain pituitary conditions, or the effects of medicines. Low levels are not by themselves proof of a specific disease.
Can I take medications or supplements before this test?
Tell your clinician about all medicines, hormone products, and supplements you use. Do not stop prescribed treatment on your own, because your clinician may recommend temporary changes or additional testing.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy