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24-Hour Urinary Creatinine Clearance

Published: August 9, 2026Updated: August 17, 2026

This test measures how well your kidneys filter waste products, specifically creatinine, over a full day using your urine.

Quick summary

["Assesses kidney function by tracking creatinine removal from your bloodstream in urine over 24 hours."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
57784-1
Short code
DHEA pre hi Dex 24h Ur-mRate
Synonyms
DHEA pre hi Dex 24h Ur-mRate
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
135
Ref high
980
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82626
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test to evaluate kidney function, diagnose kidney disease, or monitor kidney health in people with conditions like diabetes, high blood pressure, or chronic kidney disease. It helps determine how well your kidneys are filtering waste products from your blood.

How the Test Is Performed

You’ll collect all urine for 24 hours in a special container. The test measures the amount of creatinine in your urine and compares it to your blood creatinine levels to calculate clearance. Proper timing and accurate collection are critical for accurate results.

What to Expect Before the Test

No special preparation is needed, but you should drink enough fluids to produce urine throughout the day. Avoid medications that might affect kidney function unless approved by your doctor.

What the Results Mean

Results are typically expressed as a clearance rate (e.g., mL/min or mL/hr), which helps assess kidney function. Lower clearance may indicate kidney damage or disease, while higher values may suggest overhydration or other conditions.

Reference range

NCBI: DHEA-S Male 135-980 µg/dL; Female 30-260 µg/dLN/A

Specimen: urine

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is crucial for diagnosing and monitoring kidney disease, as creatinine clearance reflects how efficiently your kidneys filter waste. Abnormal results may signal impaired kidney function, requiring further evaluation or treatment adjustments.

Short name

None

Frequently asked questions

What is creatinine clearance, and how is it different from a standard blood creatinine test?
Creatinine clearance measures how well your kidneys remove creatinine (a waste product) from your blood over 24 hours using urine. A standard blood creatinine test only measures the amount in your blood, so clearance provides a more comprehensive view of kidney function by accounting for urine output.
Can I drink alcohol before this test?
Yes, you can drink alcohol, but avoid excessive amounts that might affect kidney function or urine production. Stick to your usual fluid intake unless instructed otherwise.
How long does it take to get the results of this test?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Follow up with your doctor if you have questions about your results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy