Dehydroepiandrosterone sulfate (DHEAS) – Serum
This test measures the level of dehydroepiandrosterone sulfate (DHEAS), a hormone produced by the adrenal glands that plays a role in sex hormone production and overall health.
["DHEAS helps assess adrenal function and hormone balance."]
Key facts at a glance
- LOINC
- 56508-5
- Short code
- DHEA-S 1h p chal SerPl-mCnc
- Synonyms
- DHEA-S 1h p chal SerPl-mCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 135
- Ref high
- 980
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82626
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Is DHEAS Used For?
DHEAS levels can be checked to evaluate adrenal gland health, detect hormonal imbalances, or investigate symptoms like fatigue, low libido, or irregular menstrual cycles. It may also be used in conditions like adrenal insufficiency or certain cancers.
Why Might You Need This Test?
Your healthcare provider might order a DHEAS test if you have symptoms linked to hormonal changes, such as unexplained fatigue, mood swings, or changes in body hair. It can also be part of a broader evaluation for conditions like adrenal disorders or metabolic syndrome.
How Is the Test Performed?
A blood sample is drawn from a vein in your arm. The blood is then sent to a lab for analysis. You may feel slight discomfort during the draw, but it usually takes only a few minutes.
What Does a DHEAS Test Tell You?
While DHEAS levels can indicate whether your adrenal glands are functioning properly, they don’t provide a full picture of your overall hormone health. Results are often interpreted alongside other clinical findings and symptoms.
Reference range
NCBI: DHEA-S Male 135-980 µg/dL; Female 30-260 µg/dLN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: DHEAS serves as a marker for adrenal hormone production and can help identify potential issues like adrenal insufficiency, Cushing’s syndrome, or certain cancers. However, it is not a standalone diagnostic tool and should be evaluated in context with patient history and symptoms.
Short name
DHEAS
Frequently asked questions
How often is a DHEAS test recommended?
What are the normal ranges for DHEAS?
Can lifestyle changes affect DHEAS levels?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy