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24-Hour Total Dehydroepiandrosterone Sulfate (DHEAS) Urine Test

Published: August 9, 2026Updated: August 17, 2026

This test measures the total amount of dehydroepiandrosterone sulfate (DHEAS), a hormone produced by the adrenal glands, over a 24-hour period in your urine. It helps assess adrenal function and hormone balance.

Quick summary

["This test can help diagnose or monitor conditions related to adrenal hormone production."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
34281-6
Short code
DHEA-S 24h Ur-sCnc
Synonyms
DHEA-S 24h Ur-sCnc
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
135
Ref high
980
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82626
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you have symptoms or conditions that could be linked to adrenal gland issues, such as hormonal imbalances, Cushing’s syndrome, or adrenal tumors. It may also be used to evaluate adrenal function in certain genetic conditions or before certain treatments.

What Does the Test Involve?

You will collect all urine produced in a 24-hour period in a special container. The container is typically provided by your healthcare provider. The urine sample is then sent to a lab for analysis.

What to Expect Before the Test

No special preparation is usually required, but you may need to drink extra fluids to ensure adequate urine production. Avoid using certain medications or supplements that could interfere with the test results, as instructed by your provider.

What to Expect During the Test

You will collect urine in a container for the entire 24-hour period. It’s important to keep the container clean and to discard the first urine of the morning and the last urine of the day. The sample is collected throughout the day and night.

Reference range

NCBI: DHEA-S Male 135-980 µg/dL; Female 30-260 µg/dLN/A

Specimen: urine

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

DHEAS Urine (24h)

Frequently asked questions

How long does it take to get the results of this test?
Test results are typically available within 1 to 3 business days, depending on the lab’s processing time.
What are the normal ranges for this test?
There are no specific numeric reference ranges provided here since they can vary by lab and individual. Your healthcare provider will interpret the results in relation to your clinical situation and provide guidance on what the results mean for you.
Can I take any medications before this test?
Some medications or supplements may interfere with the test results. Always inform your healthcare provider about all medications or supplements you are taking before starting this test.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy