###1: Dehydroepiandrosterone Sulfate Excretion Rate in 24-Hour Urine
###3: This test measures the amount of DHEAS, an adrenal androgen, released in urine over 24 hours. It may help evaluate adrenal hormone production when interpreted with symptoms, examination findings, and other laboratory results.
["###4: The result estimates daily urinary DHEAS excretion and is most useful when interpreted alongside the rest of your hormonal evaluation."]
Key facts at a glance
- LOINC
- 15053-2
- Short code
- DHEA-S 24h Ur-sRate
- Synonyms
- DHEA-S 24h Ur-sRate
- Category
- chemistry
- Sample
- urine
- Container
- Sterile urine container
- Units
- N/A
- Ref low
- 135
- Ref high
- 980
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82626
- Specimen volume
- 10 mL
- Stability
- Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
###5: What the Test Measures
###6: DHEAS is a form of dehydroepiandrosterone sulfate produced mainly by the adrenal glands. The 24-hour urine rate reflects the total amount excreted during a full day rather than the concentration at one moment.
###7: How the Sample Is Collected
###8: You collect all urine for exactly 24 hours into a labeled container provided by the laboratory. The start and end times, missed samples, and unusual fluid intake should be reported because they can affect the measured rate.
###9: Factors That May Influence the Result
###10: Age, sex, adrenal function, illness, and certain medicines can influence DHEAS levels. Pregnancy and use of hormone medications, supplements, or other androgen products may also affect interpretation.
###11: Why a 24-Hour Collection Is Used
###12: A 24-hour collection provides a more complete estimate of daily hormone excretion than a single urine sample. It is especially helpful when daily adrenal androgen production needs to be assessed.
Reference range
NCBI: DHEA-S Male 135-980 µg/dL; Female 30-260 µg/dLN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
###13: An elevated DHEAS excretion rate may indicate increased adrenal androgen production and can occur with androgen excess. A lower rate may reflect reduced production or normal age-related and medication-related changes. Because DHEAS alone does not establish a diagnosis, results should be interpreted by a clinician in the context of the patient’s age, sex, symptoms, examination, and other tests.
Short name
###2: 24-Hour Urine DHEAS Rate
Frequently asked questions
###14: Why must I collect urine for 24 hours?
###16: What does an elevated DHEAS rate mean?
###18: What does a low DHEAS rate mean?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy