Dehydroepiandrosterone sulfate (DHEAS)
This test measures the level of dehydroepiandrosterone sulfate (DHEAS) in your blood, a hormone produced mainly by the adrenal glands. It reflects your body’s production of androgens, which are hormones involved in sex characteristics and overall health.
["DHEAS helps assess adrenal gland function and hormone balance, often linked to conditions like adrenal insufficiency or hormonal imbalances."]
Key facts at a glance
- LOINC
- 49716-4
- Short code
- DHEA Sal-mCnc
- Synonyms
- DHEA Sal-mCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 135
- Ref high
- 980
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82626
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Is DHEAS Used For?
Doctors may order a DHEAS test to evaluate adrenal gland health, especially in cases of suspected adrenal disorders, hormonal imbalances, or conditions affecting sex hormone production. It can also be used in the diagnosis and monitoring of certain cancers, such as breast or prostate cancer, where hormone levels play a role.
How Is the Test Performed?
A blood sample is taken from a vein in your arm. You may feel a small pinch when the needle is inserted, but the procedure is quick and usually not painful. The blood is then sent to a lab for analysis.
What Does a DHEAS Test Tell You?
While DHEAS levels can vary based on age, sex, and overall health, they are not typically used alone to diagnose conditions. Instead, they are often part of a broader evaluation. For example, low levels may suggest adrenal insufficiency or other hormonal issues, while very high levels could indicate conditions like Cushing’s syndrome or certain cancers.
What Are Common Causes of Abnormal Results?
Abnormal DHEAS levels can result from a variety of factors, including adrenal gland disorders, hormonal imbalances, certain cancers, or medications that affect hormone production. Always discuss your results with your healthcare provider, as they will consider your medical history and other test results to determine the best course of action.
Reference range
NCBI: DHEA-S Male 135-980 µg/dL; Female 30-260 µg/dLN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
DHEAS
Frequently asked questions
What does a DHEAS test measure?
How often should I get a DHEAS test?
Can lifestyle changes affect DHEAS levels?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy