Dehydroepiandrosterone sulfate (DHEAS) in serum/plasma

Why Is This Test Done?

Your healthcare provider may order a DHEAS test to evaluate adrenal gland function, check for conditions like adrenal insufficiency, or assess hormone-related symptoms such as fatigue, irregular periods, or low libido. It can also be part of a broader evaluation for hormonal disorders or genetic testing.

What Does a Low or High DHEAS Level Mean?

Low DHEAS levels may suggest adrenal gland problems, such as adrenal insufficiency or early signs of adrenal fatigue. High levels could indicate overactivity of the adrenal glands or certain genetic conditions. However, results alone don’t diagnose a condition—they’re used alongside other tests and symptoms.

Common Conditions Monitored with DHEAS

DHEAS is often checked in people with suspected adrenal disorders, such as Cushing’s syndrome, Addison’s disease, or congenital adrenal hyperplasia. It may also be part of evaluations for hormonal imbalances, especially in adults experiencing unexplained fatigue or hormonal symptoms.

How Is the Test Performed?

A blood sample is taken from a vein in your arm. You may feel a slight pinch, but it usually doesn’t cause significant discomfort. The sample is sent to a lab for analysis using a specialized method to measure DHEAS concentration in your serum or plasma.