Dehydroepiandrosterone sulfate (DHEA-S) in serum/plasma
This test measures the level of dehydroepiandrosterone sulfate (DHEA-S), a hormone produced by the adrenal glands that plays a role in energy levels, stress response, and overall health.
["DHEA-S helps assess adrenal gland function and may be useful in evaluating conditions affecting hormone balance."]
Key facts at a glance
- LOINC
- 16733-8
- Short code
- DHEA sp9 p chal SerPl-mCnc
- Synonyms
- DHEA sp9 p chal SerPl-mCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 135
- Ref high
- 980
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82626
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Is DHEA-S Used For?
DHEA-S levels can help doctors diagnose or monitor conditions like adrenal insufficiency, certain cancers, or hormonal imbalances. It may also be checked during fertility evaluations or to assess aging-related hormone changes.
Why Might Your Doctor Order This Test?
Your doctor may request a DHEA-S test if you have symptoms like fatigue, weight changes, or hormonal issues. It can also be part of a broader evaluation for conditions like Cushing’s syndrome, adrenal tumors, or metabolic disorders.
What to Expect Before the Test
No special preparation is needed for this blood test. You may fast for 8–12 hours before the draw if instructed, but your doctor will confirm. Wear comfortable clothing and arrange for someone to drive you home if needed.
What Happens During the Test?
A healthcare provider will draw blood from a vein in your arm. The process takes a few minutes, and you may feel slight discomfort. The blood sample is sent to a lab for analysis.
Reference range
NCBI: DHEA-S Male 135-980 µg/dL; Female 30-260 µg/dLN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: How Does DHEA-S Fit Into Health?
Short name
DHEA-S
Frequently asked questions
How long does it take to get results from this test?
Can lifestyle changes affect DHEA-S levels?
Is DHEA-S testing covered by insurance?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy