Dehydroepiandrosterone sulfate (DHEAS) in serum/plasma
This test measures the level of dehydroepiandrosterone sulfate (DHEAS), a hormone produced primarily by the adrenal glands. It reflects your body’s natural production of this hormone, which plays a role in sex hormone regulation and overall health.
["DHEAS helps assess adrenal function and hormone balance."]
Key facts at a glance
- LOINC
- 16723-9
- Short code
- DHEA-S sp2 p chal SerPl-mCnc
- Synonyms
- DHEA-S sp2 p chal SerPl-mCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 135
- Ref high
- 980
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82626
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Is DHEAS Used For?
DHEAS testing is often used to evaluate adrenal gland health, especially in conditions like adrenal insufficiency or hyperandrogenism. It may also be checked in cases of suspected hormone imbalances, particularly in adults or during certain reproductive health evaluations.
Why Might You Need This Test?
Your healthcare provider may order a DHEAS test if you have symptoms like fatigue, low libido, irregular menstrual cycles, or signs of hormonal imbalances. It can also be part of a broader evaluation for conditions affecting the adrenal glands or sex hormone production.
How Is the Test Performed?
A blood sample is drawn from a vein, usually in your arm. The sample is then sent to a lab for analysis. The test typically takes a few days to return results, depending on lab processing times.
What Does a Low or High DHEAS Level Mean?
Results may indicate potential issues with adrenal function, but they are not diagnostic on their own. Your provider will consider your symptoms, medical history, and other test results to interpret the results accurately.
Reference range
NCBI: DHEA-S Male 135-980 µg/dL; Female 30-260 µg/dLN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: DHEAS Levels and Health Implications
Short name
DHEAS Level
Frequently asked questions
How often will I need this test?
What are the typical reference ranges for DHEAS?
Can lifestyle changes affect DHEAS levels?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy