Dehydroepiandrosterone sulfate (DHEAS) in serum/plasma
This test measures the level of dehydroepiandrosterone sulfate (DHEAS), a hormone produced by the adrenal glands that plays a role in sex hormone production and metabolism.
["DHEAS helps assess adrenal function and hormone balance, often used in conditions involving hormone disorders."]
Key facts at a glance
- LOINC
- 16724-7
- Short code
- DHEA-S sp3 p chal SerPl-mCnc
- Synonyms
- DHEA-S sp3 p chal SerPl-mCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 135
- Ref high
- 980
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82626
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Is DHEAS Used For?
DHEAS is primarily used to evaluate adrenal gland health and detect potential hormone imbalances. It can help diagnose conditions like adrenal insufficiency, certain cancers (e.g., adrenal tumors), or hormonal disorders affecting both men and women.
Why Might You Need This Test?
Your doctor may order a DHEAS test if you have symptoms like fatigue, low libido, irregular menstrual cycles, or unexplained weight changes. It may also be part of routine screening for conditions affecting hormone production or adrenal function.
Sample Collection and Preparation
A blood sample is drawn from a vein in your arm. The sample is processed into serum or plasma for testing. You may be asked to fast before the test, but this depends on your doctor’s instructions.
Test Results Interpretation
Results are not typically provided in absolute numbers alone; they are often compared to your baseline or clinical context. Your doctor will discuss what your results mean in relation to your health.
Reference range
NCBI: DHEA-S Male 135-980 µg/dL; Female 30-260 µg/dLN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: DHEAS levels can be elevated or low depending on conditions like adrenal tumors, Cushing’s syndrome, or adrenal insufficiency. It may also be used to monitor treatment responses in hormone-related disorders.
Short name
DHEAS Level
Frequently asked questions
What causes abnormal DHEAS levels?
How long does it take to get results?
Can lifestyle changes affect DHEAS levels?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy