Dehydroepiandrosterone sulfate (DHEAS) in serum/plasma
This test measures the level of dehydroepiandrosterone sulfate (DHEAS), a hormone produced primarily in the adrenal glands. It helps assess adrenal function and can be useful in evaluating conditions related to hormone balance.
["DHEAS helps doctors check adrenal health and hormone production."]
Key facts at a glance
- LOINC
- 16726-2
- Short code
- DHEA-S sp5 p chal SerPl-mCnc
- Synonyms
- DHEA-S sp5 p chal SerPl-mCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 135
- Ref high
- 980
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82626
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Is DHEAS Used For?
DHEAS levels can be checked to diagnose or monitor conditions like adrenal insufficiency, congenital adrenal hyperplasia, or hormonal imbalances. It may also be used in fertility evaluations or to assess symptoms of adrenal fatigue or other endocrine disorders.
How Is the Test Performed?
A blood sample is drawn from a vein, usually in your arm. The blood is then processed to separate serum or plasma, where the DHEAS hormone is measured using a specialized laboratory technique.
What Does a Low or High DHEAS Level Mean?
Low DHEAS levels may indicate adrenal gland problems, such as insufficient production of hormones or conditions affecting hormone metabolism. High levels could suggest overproduction by the adrenal glands or certain genetic disorders.
What Are Common Causes of Abnormal Results?
Abnormal DHEAS results can be caused by medical conditions like adrenal tumors, Cushing’s syndrome, or congenital adrenal hyperplasia. Medications, pregnancy, or certain genetic factors may also influence results.
Reference range
NCBI: DHEA-S Male 135-980 µg/dL; Female 30-260 µg/dLN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: DHEAS plays a role in hormone regulation and can signal underlying endocrine or metabolic issues. It is often used as a marker for adrenal function and may help guide treatment for conditions affecting hormone production or balance.
Short name
DHEAS Level
Frequently asked questions
Why might my doctor order a DHEAS test?
How soon will I get my DHEAS test results?
Can lifestyle changes affect DHEAS levels?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy