Dehydroepiandrosterone sulfate (DHEAS) in serum/plasma
This test measures the level of dehydroepiandrosterone sulfate (DHEAS), a hormone produced mainly by the adrenal glands. It helps assess adrenal function and hormone balance.
["DHEAS helps evaluate adrenal health and hormone production, often used in conditions like adrenal insufficiency or hormonal imbalances."]
Key facts at a glance
- LOINC
- 16728-8
- Short code
- DHEA-S sp7 p chal SerPl-mCnc
- Synonyms
- DHEA-S sp7 p chal SerPl-mCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 135
- Ref high
- 980
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82626
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Is DHEAS Used For?
DHEAS is primarily used to evaluate adrenal gland function. It can help diagnose conditions such as adrenal insufficiency, congenital adrenal hyperplasia, or hormonal disorders. Doctors may also use it to monitor treatment responses in certain cases.
Why Might Your Doctor Order This Test?
Your doctor might order a DHEAS test if you have symptoms like fatigue, low blood pressure, or hormonal imbalances. It may also be part of a broader evaluation for conditions affecting hormone production, especially in adults or during pregnancy.
How Is the Test Performed?
A blood sample is taken from a vein in your arm. The blood is then processed to separate serum or plasma, where the DHEAS level is measured using a specialized laboratory technique.
What Does a Low or High DHEAS Level Mean?
Low DHEAS levels may indicate adrenal gland problems or other hormonal imbalances. High levels could suggest conditions like Cushing’s syndrome or certain genetic disorders. Interpretation depends on clinical context and other test results.
Reference range
NCBI: DHEA-S Male 135-980 µg/dL; Female 30-260 µg/dLN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: DHEAS plays a role in hormone synthesis and stress response. Abnormal levels can signal underlying adrenal or endocrine system issues, guiding further medical evaluation or treatment adjustments.
Short name
DHEAS Level
Frequently asked questions
Could my DHEAS test results be affected by medications I’m taking?
How soon will I receive my test results?
Is fasting required for this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy