Serum or plasma concentration of dehydroepiandrosterone sulfate (DHEAS)
This test measures the amount of dehydroepiandrosterone sulfate (DHEAS), a hormone produced primarily by the adrenal glands. It reflects your body’s natural hormone production and can help assess adrenal function.
["DHEAS helps evaluate adrenal health and hormone balance, often used in conditions like adrenal insufficiency or hormone-related disorders."]
Key facts at a glance
- LOINC
- 16730-4
- Short code
- DHEA-S sp9 p chal SerPl-mCnc
- Synonyms
- DHEA-S sp9 p chal SerPl-mCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 135
- Ref high
- 980
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82626
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Is DHEAS Used For?
DHEAS testing is commonly used to diagnose or monitor conditions affecting hormone production, such as adrenal gland disorders. It may also be checked in cases of suspected premature adrenal exhaustion or to evaluate hormone levels in individuals with certain genetic or metabolic conditions.
How Is the Test Performed?
A blood sample is taken from a vein, usually in your arm. The blood is then processed to separate serum or plasma, where the DHEAS level is measured using a specialized laboratory technique.
What Might Influence Results?
Several factors can affect DHEAS levels, including age (levels typically decline with age), sex hormones, certain medications (like steroids), and health conditions such as infections or chronic illnesses. Stress, diet, and exercise can also play a role.
When Might You Need This Test?
Your healthcare provider may recommend a DHEAS test if you have symptoms like fatigue, weight changes, or hormonal imbalances. It may also be part of routine testing for individuals with adrenal disorders, metabolic syndrome, or other conditions linked to hormone dysfunction.
Reference range
NCBI: DHEA-S Male 135-980 µg/dL; Female 30-260 µg/dLN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
DHEAS levels can provide important clues about adrenal gland function and overall hormone health. Low levels may indicate adrenal insufficiency or other hormonal imbalances, while very high levels could suggest conditions like Cushing’s syndrome or certain tumors. Always discuss results with your doctor to interpret them in the context of your health.
Short name
DHEAS Level
Frequently asked questions
Why might my DHEAS test be ordered?
What are typical reference ranges?
Can lifestyle changes affect DHEAS levels?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy