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Long-chain dicarboxylic acid profile (serum/plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures levels of specific long-chain fatty acids (dicarboxylic acids) in your blood, often used to assess metabolic health or detect genetic disorders.

Quick summary

["Long-chain dicarboxylic acids can help diagnose rare genetic conditions or metabolic imbalances."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
54483-3
Short code
Dicarboxystearoylcarn Amn-sCnc
Synonyms
Dicarboxystearoylcarn Amn-sCnc
Category
chemistry
Sample
fluid
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like unexplained fatigue, muscle weakness, or developmental delays in children. It could also be part of a broader evaluation for conditions affecting fat metabolism or genetic disorders like Zellweger syndrome or peroxisomal disorders.

What to Expect Before the Test

No special preparation is typically required, but you may need to fast for a certain period before drawing blood. Follow your provider’s instructions carefully to ensure accurate results.

What the Test Involves

A blood sample will be taken from a vein in your arm by a healthcare professional. This is a standard procedure that usually takes a few minutes. You may feel a slight pinch, but it should not cause significant discomfort.

What the Results Mean

The results will show the concentration of specific long-chain dicarboxylic acids in your blood. Elevated levels may indicate metabolic disorders, while normal levels help rule out certain genetic conditions. Your provider will interpret these results in the context of your overall health and symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

None

Frequently asked questions

What could cause abnormal results?
Abnormal levels of long-chain dicarboxylic acids may suggest underlying metabolic disorders, such as peroxisomal deficiencies or other genetic conditions affecting fat metabolism. These conditions can impact how your body processes certain nutrients and energy production.
How might this test help my healthcare provider?
This test helps identify whether certain genetic or metabolic disorders are present, guiding treatment plans or further diagnostic steps. Early detection can lead to better management and support for conditions like Zellweger syndrome or other peroxisomal disorders.
Is this test painful or uncomfortable?
The blood draw itself is generally mild discomfort, similar to receiving a standard blood test. Most people experience minimal pain or bruising afterward. If you have a fear of needles, let your healthcare provider know so they can offer alternatives or reassurance.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy