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Ethylene Glycol Concentration (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of ethylene glycol, a toxic substance found in antifreeze and other products, in your blood. It helps doctors diagnose poisoning or monitor exposure.

Quick summary

["Detecting ethylene glycol poisoning early can save your life."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
34436-6
Short code
Diethylene Glycol SerPl-mCnc
Synonyms
Diethylene Glycol SerPl-mCnc
Category
glucose
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Ethylene glycol is a poison that can cause severe health problems if ingested, inhaled, or absorbed through the skin. Your body breaks it down into toxic byproducts that can damage organs like the kidneys and liver. This test helps identify if you’ve been exposed to ethylene glycol, which can occur from accidental ingestion (e.g., drinking antifreeze) or occupational hazards.

How the Test Works

Your blood sample is tested using a specialized method (likely immunoassay or enzymatic analysis) to measure the exact amount of ethylene glycol present. This helps healthcare providers determine the severity of exposure and guide treatment, such as antidotes or supportive care.

What to Expect Before the Test

No special preparation is needed for this test. You may have a small needle inserted into your arm to draw blood, similar to other routine blood tests. If you’ve recently consumed alcohol or certain medications, let your doctor know, as they may affect results or your safety during testing.

Possible Results and Next Steps

If your result is above normal levels, your doctor will assess your symptoms, medical history, and other test results to determine the cause. Treatment may include antidotes (like fomepizole), fluids to support kidney function, or monitoring for organ damage. Follow-up tests may be needed to track your recovery.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Ethylene Glycol Level

Frequently asked questions

What does a high level of ethylene glycol mean?
A high level suggests recent exposure to ethylene glycol, which can lead to symptoms like confusion, nausea, vomiting, rapid breathing, or even coma. Doctors use this test to confirm poisoning and guide urgent treatment. Low or normal levels mean no acute poisoning is detected, but ongoing monitoring may still be necessary if you’ve had exposure.
How soon will I get my results?
Results are typically available within 24 hours, but timing depends on lab processes. Your doctor will contact you to discuss the findings and next steps, especially if levels are elevated.
Can I drink alcohol before this test?
It’s best to avoid alcohol for 24 hours before testing, as it may interfere with blood collection or affect test accuracy. However, your doctor will advise you based on your specific situation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy