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Oxygen saturation in arterial blood (SaO₂) measured via pulse oximetry or blood gas analysis

Published: August 9, 2026Updated: August 16, 2026

This test measures how much oxygen is bound to hemoglobin in your blood when it reaches your arteries, helping assess lung function and oxygen delivery to tissues.

Quick summary

["Evaluates oxygen levels in your blood to check for lung or heart issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
2024-8
Short code
dis CO2 Plas-sCnc
Synonyms
dis CO2 Plas-sCnc
Category
chemistry
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Ref low
22
Ref high
28
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82374
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why is this test done?

Your healthcare provider may order this test if you have symptoms like shortness of breath, fatigue, or a history of lung diseases (e.g., COPD, asthma). It’s also used during surgeries, anesthesia, or in critical care settings to monitor oxygen levels in real time.

How is the test performed?

A small sensor is placed on your finger, toe, or ear lobe to measure oxygen saturation. Alternatively, blood may be drawn from an artery (arterial blood gas) for more detailed results, though this is less common for routine SaO₂ checks.

What does a low or high result mean?

Low SaO₂ (below expected range) may indicate poor lung function, anemia, or conditions like pneumonia or heart failure. High SaO₂ (above expected range) is rare but could suggest certain blood disorders or technical errors in measurement.

Common conditions affecting results

Conditions like chronic obstructive pulmonary disease (COPD), sleep apnea, or anemia can lower SaO₂. Conversely, certain medications (e.g., nitroglycerin) or high altitudes may temporarily raise it. Always discuss your symptoms and medications with your provider.

Reference range

Adult: 22-28 mmol/LN/A

Specimen: plasma

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical significance: SaO₂ is critical for diagnosing and managing respiratory and cardiovascular diseases. It helps guide treatments like oxygen therapy or adjustments to medications that affect oxygen transport.

Short name

Arterial oxygen saturation (SaO₂)

Frequently asked questions

Will I feel any discomfort during the test?
Most pulse oximetry tests are painless and quick. If blood is drawn, you may feel a slight pinch, but it’s minimal. Arterial blood draws require a brief moment of pressure but are less invasive than other blood tests.
How soon will I get my results?
Results from pulse oximetry are usually available immediately. If blood is drawn, results may take 1–2 hours, depending on lab processing. Your provider will discuss them with you during your visit.
Can I eat or drink before this test?
No special preparation is needed for pulse oximetry. For arterial blood gas tests, fasting may be required if other blood tests are also being done, but this is rare for SaO₂ alone.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy