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Disco2 RBC Substance Concentration (Serum/Plasma)

Published: August 9, 2026Updated: August 17, 2026

This test measures the concentration of a specific substance found in red blood cells (RBCs) using a serum or plasma sample. It may be used to assess metabolic, biochemical, or functional aspects of RBCs.

Quick summary

["Understanding your RBC substance levels can help identify potential health concerns related to red blood cells."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
2025-5
Short code
dis CO2 RBC-sCnc
Synonyms
dis CO2 RBC-sCnc
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
22
Ref high
28
Critical range
2 N/A – 7 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82374
SNOMED
900000000000003001
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like fatigue, unusual bleeding, or if they suspect conditions affecting RBCs, such as anemia, inherited blood disorders, or metabolic syndromes. It could also be part of a broader evaluation for unexplained lab abnormalities.

What to Expect Before the Test

No special preparation is typically needed. You may fast for 8–12 hours before the test if instructed, but this depends on the lab’s protocol. Bring any medications you’re currently taking to your appointment.

How the Test Works

A small blood sample is drawn from a vein in your arm. The blood is processed to separate serum or plasma, which is then analyzed to measure the concentration of the substance in RBCs using advanced laboratory techniques.

What the Results Mean

Results are compared to reference ranges specific to the substance measured. Abnormal levels may indicate underlying conditions that require further medical evaluation, such as genetic disorders, enzyme deficiencies, or exposure to certain substances.

Reference range

Adult: 22-28 mmol/LN/A

Specimen: whole-blood

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

RBC Substance Level (Serum/Plasma)

Frequently asked questions

What causes abnormal RBC substance levels?
Abnormal RBC substance levels may result from genetic factors, certain medications, chronic illnesses, or exposure to toxins. Your healthcare provider will review your medical history and other test results to determine the cause.
How often should I get this test?
Frequency depends on your health status and symptoms. Routine screening isn’t typically recommended unless advised by your doctor. Follow-up testing may be scheduled if initial results are concerning or if you develop new symptoms.
Can lifestyle changes affect this test?
Some lifestyle factors, like diet or hydration, may indirectly influence blood chemistry but don’t directly alter RBC substance concentrations. Avoiding alcohol or certain medications before testing can help ensure accurate results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy