Lactate concentration in cerebrospinal fluid
This test measures the level of lactate, a byproduct of energy production in your brain and spinal cord, found in cerebrospinal fluid (the fluid surrounding your brain and spinal cord).
["Lactate in CSF can help diagnose conditions affecting brain metabolism or blood flow."]
Key facts at a glance
- LOINC
- 75040-6
- Short code
- D-Lactate CSF-sCnc
- Synonyms
- D-Lactate CSF-sCnc
- Category
- chemistry
- Sample
- csf
- Container
- Sterile tube
- Units
- N/A
- Critical range
- — – 4 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 1-2 mL
- Stability
- Immediate analysis required, Refrigerated: 1h
- Hemolysis max
- 200
- TAT
- 4–24 hours
- Order
- routine
Why Might This Test Be Ordered?
Your healthcare provider may order this test if you have symptoms like severe headaches, confusion, seizures, or neurological issues that could suggest conditions like metabolic disorders, infections, or bleeding in the brain. It may also be used to monitor patients with known brain disorders or after certain surgeries.
What Does a High or Low Level Mean?
Elevated lactate levels in CSF can indicate conditions such as brain hypoxia (lack of oxygen), infections, or certain metabolic disorders. Lower-than-expected levels might suggest rare conditions or errors in test interpretation, so results should always be reviewed by a healthcare professional.
How Is This Test Performed?
A small sample of cerebrospinal fluid is collected through a procedure called a lumbar puncture (spinal tap). The fluid is then analyzed in a lab to measure lactate concentration using specialized techniques.
What Should You Expect Before the Test?
You may be asked to fast for a short period before the test, but this is not always required. Avoid caffeine or alcohol 24 hours before the procedure. Inform your doctor about any medications you’re taking, as some may affect results.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
CSF Lactate
Frequently asked questions
How long does it take to get results from this test?
Can lifestyle changes affect this test result?
Is there any risk or discomfort associated with this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy