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Fibrinogen (Serum) Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of fibrinogen, a protein in your blood that helps form clots.

Quick summary

["Fibrinogen helps control bleeding and supports blood clot formation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
74624-8
Short code
DMA 16:0/C16:0 Fib
Synonyms
DMA 16:0/C16:0 Fib
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to check for bleeding disorders, monitor blood clotting problems, or evaluate liver function, as fibrinogen is produced in the liver. It can also help assess risks for conditions like deep vein thrombosis or stroke.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into a vein (usually in your arm) to draw blood. If you’re on blood thinners, let your doctor know before the test.

What the Results Mean

Results are compared to a general reference range, but exact values can vary by lab. Low levels may suggest bleeding disorders or liver issues, while high levels could indicate inflammation or pregnancy.

Common Conditions Linked to Fibrinogen Levels

Abnormal fibrinogen levels may be linked to bleeding disorders (like hemophilia), clotting disorders (like thrombophilia), or conditions affecting liver function (like cirrhosis). It can also be influenced by pregnancy, infections, or inflammatory diseases.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Fibrinogen plays a critical role in blood clotting and wound healing. Low levels can increase bleeding risk, while high levels may raise clot formation risks. Your doctor will interpret results in the context of your overall health.

Short name

Fibrinogen

Frequently asked questions

Why did my doctor order this test?
Your doctor may have suspected bleeding issues, liver problems, or other conditions affecting blood clotting. They may also be monitoring a known condition like pregnancy or inflammation.
What does a low or high fibrinogen level mean?
Low levels may signal bleeding risks or liver dysfunction, while high levels could indicate inflammation or pregnancy. Your doctor will discuss these findings with you based on your symptoms and medical history.
Can diet or lifestyle affect fibrinogen levels?
Dietary factors like high-fat foods or certain medications (e.g., blood thinners) may influence fibrinogen, but results are typically interpreted in the context of your overall health. Avoid heavy meals 24 hours before testing if instructed.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy