Skip to content

Fibrinogen Mass Concentration (Serum or Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of fibrinogen, a protein in your blood that helps blood clot. Low levels may increase bleeding risk, while high levels could signal conditions like inflammation or liver disease.

Quick summary

["Fibrinogen helps control bleeding and may reflect underlying health conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
74626-3
Short code
DMA 16:0 Fib-mCnt
Synonyms
DMA 16:0 Fib-mCnt
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to check for bleeding disorders, monitor conditions like liver disease or inflammation, or evaluate blood clotting after surgery or trauma.

When Might You Need This Test?

You might need this test if you have symptoms like easy bruising, prolonged bleeding, unexplained fatigue, or if your doctor suspects a clotting disorder or liver issue.

How Is the Test Performed?

A blood sample is taken from a vein, usually in your arm. The blood is sent to a lab where it is processed to separate serum or plasma for testing.

What Do Results Mean?

Results are compared to standard ranges, but exact values can vary by lab. Low levels may indicate bleeding risks, while high levels could signal conditions like infection, inflammation, or liver problems.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Fibrinogen plays a critical role in blood clotting. Abnormal levels can indicate bleeding disorders, clotting issues, or systemic conditions like liver disease or infections. Your doctor will interpret results in the context of your overall health and symptoms.

Short name

Fibrinogen Level

Frequently asked questions

What causes low fibrinogen levels?
Low fibrinogen can be caused by liver disease, severe infections, blood loss, or certain medications. It may also occur in conditions like disseminated intravascular coagulation (DIC).
What causes high fibrinogen levels?
High fibrinogen levels are often seen in inflammatory conditions (e.g., rheumatoid arthritis), infections, or liver disease. Rarely, it may be genetic or linked to certain cancers.
Can lifestyle changes affect fibrinogen levels?
While diet and exercise can influence overall health, they may not directly alter fibrinogen levels. Your doctor will focus on managing underlying conditions if needed.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy