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DNA Index (Serum/Plasma) by Flow Cytometry (Probe-Based)

Published: August 9, 2026Updated: August 16, 2026

This test measures the DNA content of cells in your blood, often used to assess genetic or cellular abnormalities.

Quick summary

["Helps doctors evaluate potential genetic or cellular changes in your blood sample."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
34975-3
Short code
DNA Index SerPl FC-aCnc
Synonyms
DNA Index SerPl FC-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The DNA Index test quantifies the amount of DNA in cells from your blood sample. It compares the DNA content to a standard reference (typically diploid cells, which have two sets of chromosomes). Variations may indicate abnormal cell division, such as in certain cancers or genetic disorders.

Why Might You Need This Test?

This test may be ordered to investigate suspected genetic conditions, monitor cellular activity in blood cancers (e.g., leukemia), or evaluate conditions linked to abnormal cell proliferation.

How Is the Test Performed?

A blood sample is taken, and cells are analyzed using flow cytometry with a fluorescent probe. The probe binds to DNA, allowing measurement of DNA content per cell.

What Are Common Uses?

Common uses include diagnosing or monitoring conditions like chromosomal abnormalities, certain cancers, or genetic syndromes where cell division is irregular.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: The DNA Index test is particularly useful in oncology for identifying cells with abnormal DNA content, such as in lymphoma, leukemia, or solid tumors. It can help determine the aggressiveness of a condition or guide treatment decisions.

Short name

DNA Index Test

Frequently asked questions

What does a DNA Index test result mean?
A result may be described as hypodiploid (less DNA), diploid (normal), hyperdiploid (more DNA), or tetraploid (four sets of chromosomes). Interpretation depends on clinical context and may require comparison to baseline or other tests.
How long does it take to get results?
Results are typically available within 24 to 72 hours, depending on lab processing times and complexity of the sample.
Is this test painful or invasive?
No, this test involves a simple blood draw, similar to other routine blood tests. You may feel slight discomfort, but it is generally well-tolerated.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy