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DNA Index (Cell Cycle Analysis) from Specimen Fluid (Cellular)

Published: August 9, 2026Updated: August 16, 2026

This test measures the DNA content of cells in a sample, often used to assess cell division patterns in tissues like tumors or biopsies.

Quick summary

["Helps doctors understand how cells are dividing, which can guide treatment decisions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
30912-0
Short code
DNA Index Spec FC-aCnc
Synonyms
DNA Index Spec FC-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is a DNA Index?

A DNA index compares the amount of DNA in cells to a reference standard (typically diploid cells, which have two sets of chromosomes). It’s often used in cytogenetics or pathology to evaluate cell proliferation, such as in cancer diagnosis.

Why Might You Need This Test?

Doctors may order this test to diagnose or monitor conditions like cancer, where abnormal cell division is common. It can help determine if a tumor is benign or malignant or guide treatment planning.

How Is the Sample Collected?

The test typically uses a fluid sample containing cells, such as from a fine-needle biopsy, surgical sample, or cytology smear. The lab processes the sample to analyze cell DNA content under a microscope.

What Does the Result Mean?

A result may be reported as a numerical value (e.g., 1.5) or as a ratio compared to normal cells. Higher values often suggest rapid cell division, which can be seen in cancers. Your doctor will interpret the result in the context of your medical history and symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: DNA Index in Cancer Diagnosis and Monitoring

Short name

DNA Index

Frequently asked questions

How often will I need this test?
The frequency depends on your treatment plan. If you’re being monitored for cancer, your doctor may order this test periodically to check for changes in cell division patterns.
What are the possible risks or side effects of this test?
There are usually no risks associated with the sample collection itself, but minor discomfort (e.g., bruising or soreness) may occur at the injection site. If the sample is taken from a biopsy, there could be temporary pain or swelling.
Can I prepare for this test in any way?
No special preparation is usually needed unless your doctor specifies otherwise. Follow any instructions they provide, such as fasting or avoiding certain medications, to ensure accurate results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy