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Total IgE (Immunoglobulin E) Level

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin E (IgE) in your blood. IgE is a type of antibody that plays a role in allergic reactions and responses to certain allergens.

Quick summary

["IgE levels help identify allergies or immune system sensitivities."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
61333-1
Short code
Dog Dander IgE/IgE total %
Synonyms
Dog Dander IgE/IgE total %
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your doctor may recommend this test if you have symptoms like sneezing, itching, hives, or asthma that suggest allergies. It can also be used to evaluate conditions like allergic rhinitis, eczema, or certain types of asthma, or to check for reactions to specific allergens.

What to Expect Before the Test

No special preparation is needed for this blood test. You may have a small needle inserted into your arm to draw a small amount of blood, similar to a routine blood draw.

What the Test Results Mean

IgE levels can vary widely among individuals. Higher than normal levels may indicate allergies or hypersensitivity to certain substances. However, even normal IgE levels don’t rule out allergies entirely.

Common Conditions Monitored or Diagnosed

This test is often used to diagnose allergies, including food allergies, seasonal allergies, or allergic rhinitis. It can also help assess conditions like atopic dermatitis (eczema) or allergic asthma.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated IgE levels often signal an allergic reaction or an overactive immune response to allergens. While IgE testing can confirm suspected allergies, it’s not definitive on its own. Other tests, like skin prick tests or specific IgE antibody tests, may be needed for a full evaluation.

Short name

IgE Total

Frequently asked questions

What does a high IgE level mean?
A high IgE level may suggest an allergic reaction or an immune response to allergens, but it doesn’t always indicate the specific cause. It can help guide further testing or treatment plans.
Can IgE levels change over time?
Yes, IgE levels can fluctuate depending on exposure to allergens, immune health, and underlying conditions. They may also change with treatment, such as allergy immunotherapy.
Is IgE testing painful?
The test involves a small needle insertion for blood draw, which is generally quick and minimally uncomfortable. Most people experience only mild discomfort afterward.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy