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Serum Creatinine (Creatinine Level)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood to assess kidney function.

Quick summary

["Helps check how well your kidneys filter waste from your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
19226-0
Short code
DO-Hgb MFr BldC
Synonyms
DO-Hgb MFr BldC
Category
hematology
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
12
Ref high
17.5
Critical range
7 N/A – 20 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85018
SNOMED
900000000000003004
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What Is Creatinine?

Creatinine is a byproduct of muscle breakdown that your kidneys normally filter out of your blood. High levels may indicate kidney problems, while low levels could suggest muscle disorders or other conditions. This test is often used alongside other kidney function tests to get a full picture.

Why Might You Need This Test?

Your doctor may order a creatinine test to evaluate kidney health, especially if you have symptoms like swelling, fatigue, or changes in urine output. It’s also used before surgeries, during pregnancy, or if you have conditions like diabetes or high blood pressure that affect kidney function.

How Is the Test Done?

A blood sample is taken from a vein in your arm. The sample is sent to a lab where it’s analyzed to measure creatinine levels. No special preparation is usually needed, but you may be asked to avoid certain medications or foods for a short time if instructed by your doctor.

What Are Common Results?

Results are compared to a general reference range, though individual ranges can vary. High creatinine levels may signal impaired kidney function, while very low levels might warrant further investigation into muscle health or other conditions.

Reference range

Adult males: 13.5-17.5 g/dL; Females: 12.0-16.0 g/dLN/A

Specimen: whole-blood

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Kidney Function and Beyond

Short name

Creatinine

Frequently asked questions

How often will I need this test?
This test is often performed once or twice a year for people with chronic kidney disease or risk factors like diabetes or hypertension. If you have no known issues, it may be done less frequently, but your doctor will determine the best schedule for you based on your health.
Will I feel any pain or discomfort during the blood draw?
Most people experience only a slight pinch or sting when the needle is inserted. Afterward, there may be a small bruise or tenderness at the site, but this usually goes away quickly. If you’re nervous, let your healthcare provider know—they can offer ways to make it more comfortable.
Can I eat or drink normally before this test?
You can eat and drink as usual unless your doctor specifies otherwise. Some tests may require fasting, but creatinine tests do not. Always follow your doctor’s instructions to avoid any unnecessary delays or inaccuracies in results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy