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Serum Creatinine (Creatinine Level)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood. It helps assess how well your kidneys are filtering waste.

Quick summary

["Kidney function check: creatinine helps determine if your kidneys are working properly."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
28368-9
Short code
DONTHAVETOKEEPFIGHTING
Synonyms
—
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
reported-living-hiv
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does Creatinine Tell Us About My Health?

Creatinine levels can indicate how well your kidneys are filtering blood. Higher levels may suggest kidney problems, while lower levels might indicate muscle mass or hydration status. This test is often used alongside other kidney function tests to diagnose conditions like chronic kidney disease or acute kidney injury.

Why Might My Doctor Order This Test?

Your doctor may order a creatinine test to monitor kidney health before or after certain treatments, check for kidney disease, evaluate symptoms like fatigue or swelling, or assess how well medications are being processed by your kidneys.

What Can Affect Creatinine Levels?

Several factors can influence creatinine levels, including muscle mass (more muscle generally means higher levels), hydration status, diet (especially protein intake), and certain medications. Blood tests are usually taken after fasting for about 8–12 hours to reduce variability from recent meals or fluids.

How Is This Test Performed?

A small blood sample is drawn from a vein, usually in your arm. The sample is sent to a lab where it is analyzed to measure creatinine concentration. Results are typically available within a few days.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Creatinine

Frequently asked questions

How is creatinine used in diagnosing kidney disease?
Creatinine is often used alongside other tests like blood urea nitrogen (BUN) to calculate the **glomerular filtration rate (GFR)**, a key measure of kidney function. Elevated creatinine levels may signal reduced kidney function, but they can also be influenced by other factors like dehydration or muscle issues. Your doctor will interpret results in the context of your overall health and other test results.
What if my creatinine level is higher than expected?
Higher creatinine levels may indicate kidney problems, but they can also be caused by dehydration, recent heavy exercise, or high muscle mass. If your doctor suspects kidney issues, they may order additional tests or follow-up visits to investigate further.
Can diet affect creatinine levels?
Yes, diet can influence creatinine levels. High-protein diets may temporarily increase creatinine levels, while dehydration can raise them as well. Your doctor may recommend specific dietary adjustments or timing of tests if needed.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy