Free Fetoprotein (AFP) in Serum for Prenatal Screening

Why This Test Is Done

Your healthcare provider may recommend this test during your first or second trimester to check for potential birth defects, such as spina bifida or other neural tube defects, or to assess risks for chromosomal abnormalities like Down syndrome. It’s often part of a broader prenatal screening process.

What to Expect Before the Test

You’ll typically have a simple blood draw from a vein in your arm. No special preparation is needed, but inform your provider if you’re on blood-thinning medications or have a history of bleeding disorders.

What the Results Mean

Results are usually interpreted alongside other prenatal tests (like nuchal translucency screening or maternal blood tests). Elevated levels may signal higher risk for certain birth defects, while very low levels could raise concerns for other conditions. Your provider will discuss findings with you.

Common Reasons for Testing

This test is commonly ordered when you’re pregnant to monitor fetal development and identify potential risks early. It’s especially recommended if you’re at higher risk due to factors like maternal age, family history, or previous pregnancy complications.