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Serum/plasma concentration of a substance measured by immunoassay (e.g., antibody screening)

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of certain antibodies in your blood, often used to screen for infections, autoimmune conditions, or other immune-related issues.

Quick summary

["A simple blood test to detect antibodies that may signal an immune response or underlying health condition."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
101243-4
Short code
DPPX Ab SerPl Ql IF
Synonyms
DPPX Ab SerPl Ql IF
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

This test measures the level of specific antibodies in your serum or plasma. Antibodies are proteins produced by your immune system in response to infections, vaccines, or other triggers. The test may identify whether your body has detected and fought off a pathogen, or if there is an ongoing immune response to a condition like lupus, rheumatoid arthritis, or an infection.

Common Uses

Screening for infections (e.g., viral, bacterial, or parasitic), detecting autoimmune diseases (e.g., lupus, rheumatoid arthritis), evaluating immune system function, or confirming exposure to certain substances (e.g., toxins, vaccines).

How the Test Works

Blood is drawn and processed to separate serum or plasma. The sample is then analyzed using an immunoassay method, which detects and quantifies specific antibodies bound to a target antigen. This process may involve color changes, fluorescence, or other signals captured by the lab equipment.

Sample Collection and Preparation

A small amount of blood is collected via a needle, typically from a vein in your arm. The blood is then processed to remove cells, leaving behind serum or plasma. This liquid is stored and sent to the lab for testing.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Serum/plasma antibody screening

Frequently asked questions

Why might my doctor order this test?
Your doctor may recommend this test if you have symptoms of an infection (e.g., fever, fatigue), suspected autoimmune disease, or if you’ve been exposed to a known pathogen or vaccine. It can also help monitor immune responses in chronic conditions or guide treatment decisions.
What does a positive result mean?
A positive result indicates the presence of antibodies against a specific antigen. This could mean you’ve been exposed to an infection, vaccinated, or have an autoimmune condition triggering an immune response. However, false positives can occur, so follow-up testing may be needed.
How soon will I get results?
Results are typically available within 1–3 business days, depending on lab processing times. Your doctor will discuss the findings with you and explain next steps, if needed.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy