Total Protein with Albumin/Globulin Ratio (Serum)
This test measures your total protein levels in blood and evaluates the balance between albumin and globulin proteins, which can help identify conditions affecting protein synthesis, breakdown, or kidney function.
["Assessing protein balance may reveal kidney issues or liver disorders."]
Key facts at a glance
- LOINC
- 94676-4
- Short code
- DPPX IgG Ser Ql CBA IFA
- Synonyms
- DPPX IgG Ser Ql CBA IFA
- Category
- coagulation
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- cba-ifa
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Matters
Your body relies on proteins like albumin and globulin for many vital functions, including maintaining fluid balance, supporting immunity, and transporting nutrients. Abnormal levels can signal underlying health problems, such as chronic kidney disease, liver disease, or malnutrition.
What to Expect Before the Test
No special preparation is needed. You may eat and drink normally before your blood draw. Your healthcare provider will explain the process and any potential discomfort.
What the Results Mean
While specific reference ranges vary by lab, a protein profile helps identify whether your albumin and globulin levels are within expected ranges. Low albumin may indicate liver or kidney issues, while abnormal globulin levels could suggest immune system disorders or infections.
Common Conditions Monitored
This test is often used to monitor kidney function (e.g., chronic kidney disease), liver health (e.g., cirrhosis), or conditions affecting protein metabolism (e.g., malnutrition, inflammatory diseases). It may also help diagnose or track conditions like nephrotic syndrome or multiple myeloma.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical significance: Protein balance is critical for organ function and immune defense. Low albumin may reflect poor liver or kidney function, while elevated globulins could signal chronic inflammation, infections, or autoimmune disorders. Early detection helps guide treatment decisions.
Short name
Protein profile
Frequently asked questions
What causes abnormal protein levels in this test?
How often should I get this test?
Can diet affect my protein test results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy