Drug-Induced Neutrophil Activation Protein (Serum/Plasma)
This test measures a protein released by white blood cells (neutrophils) when they become activated by certain medications, which may indicate an adverse drug reaction.
["This test helps identify if your body’s immune response is unusually strong to specific drugs you’re taking."]
Key facts at a glance
- LOINC
- 72909-5
- Short code
- Drug induced neutrophil Ab pnl SerPl
- Synonyms
- Drug induced neutrophil Ab pnl SerPl
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your doctor may recommend this test if you’ve experienced symptoms like fever, rash, or organ involvement (such as liver or kidney problems) while taking certain medications. It’s also used to monitor patients with known drug hypersensitivity reactions.
What to Expect Before the Test
No special preparation is needed. You’ll provide a blood sample, usually drawn from a vein in your arm. The sample is collected in a tube that separates serum or plasma from blood cells for testing.
What the Test Results Mean
Higher than expected levels of this protein may suggest your neutrophils are overactive due to drug exposure. Your doctor will interpret results in the context of your symptoms, medications, and medical history.
Common Medications Linked to This Reaction
Some drugs that may trigger this response include antibiotics (e.g., sulfonamides), anticonvulsants (e.g., carbamazepine), and certain chemotherapy agents. Always inform your doctor about all medications you’re taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Elevated levels of this protein can signal a severe immune-mediated reaction, such as drug-induced hypersensitivity syndrome (DIHS) or drug rash with eosinophilia and systemic symptoms (DRESS). Early detection can prompt adjustments to your medication or treatment plan to prevent complications.
Short name
Drug-Induced Neutrophil Activation Marker
Frequently asked questions
What triggers this test?
How soon will I get results?
Can I stop taking my medication before the test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy