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Drug Use Screening in Pregnant Mother (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test checks for certain drugs in your blood or urine to ensure your health and your baby’s safety during pregnancy.

Quick summary

["Screening helps identify substances that could harm your pregnancy."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
89495-6
Short code
Drug use preg Mother
Synonyms
Drug use preg Mother
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you have concerns about substance use, if you’re in a high-risk pregnancy group, or if you’re part of a prenatal screening program. It helps monitor for substances like alcohol, nicotine, or other illicit drugs that could affect fetal development.

What Does the Test Involve?

The test typically involves a blood draw (serum/plasma) or a urine sample. The lab analyzes the sample using immunoassay methods to detect the presence of specific drugs or their metabolites.

What Are Common Drugs Monitored?

Common substances screened for include alcohol, nicotine, marijuana, cocaine, opioids (like heroin or prescription painkillers), and other illicit drugs. Some tests may also check for over-the-counter medications or supplements if they could be harmful.

What Does a Positive Result Mean?

A positive result means the drug or its metabolites were detected in your sample. This does not necessarily mean you’re at risk, but it may prompt further discussion with your healthcare provider about substance use habits and safety during pregnancy.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Detecting drug use during pregnancy is critical because certain substances can cross the placenta and affect fetal development. Early identification allows for counseling, support, and interventions to reduce risks to both you and your baby. Some drugs may increase the risk of birth defects, preterm labor, or low birth weight.

Short name

Drug Screening (Pregnancy)

Frequently asked questions

How Often Will I Need This Test?
The frequency depends on your healthcare provider’s recommendations. Some women may need screening multiple times during pregnancy, especially if they have a history of substance use or are at higher risk.
What Happens If My Test Results Are Positive?
If your test is positive, your healthcare provider will discuss the results with you. They may recommend additional testing, counseling, or referrals to support services to help manage substance use safely during pregnancy.
Can I Stop Taking Medications or Supplements Before the Test?
Yes, follow your healthcare provider’s instructions carefully. Some medications or supplements may show up in the test, so they may advise you to stop taking them temporarily or clarify which ones to avoid.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy