Skip to content

Serum Creatinine (Standard Method)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood. It helps assess how well your kidneys are filtering blood.

Quick summary

["A creatinine test checks kidney function by measuring waste in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
97641-5
Short code
dRVVT/dRVVT cfm p DOAC neut Norm PPP-Rto
Synonyms
dRVVT/dRVVT cfm p DOAC neut Norm PPP-Rto
Category
chemistry
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Fasting
true
Population
adult
Sex
all
Age range
18–65 years
Method
coag
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Your kidneys normally filter waste products, including creatinine, from your blood. High levels may indicate poor kidney function or damage, while low levels could suggest muscle breakdown or other conditions. This test is often used alongside other kidney function tests to monitor kidney health, especially in people with diabetes, high blood pressure, or a history of kidney disease.

What to Expect Before the Test

No special preparation is needed for this test. You may have a small needle inserted into your arm or vein to draw blood. If you’re on a low-protein diet or have recently exercised heavily, your doctor may advise timing your test to avoid potential variations in results.

Common Causes of Abnormal Results

Elevated creatinine levels may signal kidney problems, dehydration, or conditions like muscle disorders or heart failure. Low levels might suggest dehydration, muscle loss, or certain liver or heart conditions. Always discuss any symptoms or concerns with your healthcare provider.

How Results Are Interpreted

Results are typically compared to a reference range provided by your lab. While ranges can vary slightly by lab, they help identify whether your levels are within normal limits or if further investigation is needed.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Creatinine

Frequently asked questions

What might cause my creatinine levels to be high?
High creatinine levels can result from kidney disease, dehydration, severe muscle damage, or conditions that affect blood flow to the kidneys. If you notice unexplained fatigue, swelling, or changes in urine output, talk to your doctor about possible causes and next steps.
Could my diet affect this test?
Yes, diet can influence creatinine levels. High-protein foods or intense exercise may temporarily increase muscle breakdown, raising creatinine. Your doctor may recommend timing your test after a period of normal activity or diet to get the most accurate reading.
What should I do if my creatinine is outside the normal range?
If your results are abnormal, your healthcare provider will review them with you and may recommend additional tests, like urine tests or imaging, to determine the cause. Follow-up may include monitoring kidney function over time or adjusting medications if needed.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy