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Vitamin D binding protein (DBP) concentration, serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of a protein in your blood that helps transport vitamin D. It’s often checked alongside vitamin D levels to assess overall vitamin D status and metabolism.

Quick summary

["This test helps doctors evaluate how your body processes vitamin D and may support diagnosis of related conditions like vitamin D deficiency or disorders of vitamin D metabolism."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
43397-9
Short code
dRVVT imm NP PPP
Synonyms
dRVVT imm NP PPP
Category
chemistry
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
coag-dilute-russell-viper-venom-induced-factor-substitution-immediately-after-addition-of-normal-plasma
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters in Your Health

Vitamin D binding protein (DBP) plays a key role in transporting vitamin D through your bloodstream. While vitamin D itself is crucial for bone health and immune function, DBP ensures it’s available where needed. Your doctor may order this test if they suspect vitamin D deficiency, kidney or liver issues, or genetic disorders affecting vitamin D metabolism.

What to Expect Before the Test

No special preparation is needed for this test. You’ll have a small needle inserted into your arm or vein to draw blood. If you’re nervous, let your healthcare provider know—they can offer comfort measures. Avoid alcohol for 24 hours before testing if instructed, as it may affect blood composition.

Common Reasons for This Test

Doctors may order this test if you have symptoms like fatigue, bone pain, or frequent infections, which could signal vitamin D deficiency or related conditions. It’s also used in research or monitoring certain genetic disorders. Your doctor will discuss the reason with you before ordering it.

What the Results Mean

Results help assess how well your body is using vitamin D. High levels may indicate overproduction or certain genetic conditions, while low levels could suggest vitamin D deficiency or kidney/liver problems. Your doctor will interpret results in the context of your overall health and symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Vitamin D Binding Protein

Frequently asked questions

How often should I get this test?
This test is usually done as needed, based on your symptoms, medical history, or doctor’s recommendations. For example, pregnant women, older adults, or those with chronic conditions may need it more frequently. Follow your healthcare provider’s advice for timing and frequency.
Does this test affect my vitamin D levels?
No, measuring DBP itself does not change your vitamin D levels. However, if your doctor finds abnormal results, they may recommend vitamin D supplements or adjustments to your diet to address any underlying issues.
Can I eat or drink anything before the blood draw?
Typically, you can eat and drink normally unless your doctor specifies otherwise. Some tests require fasting, but this one does not. Always check with your healthcare provider before the appointment to confirm any restrictions.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy