D-dimer (serum/plasma, quantitative immunoassay)
This test measures the D-dimer protein, a breakdown product formed when blood clots dissolve. It helps assess whether abnormal clotting or clot-dissolving processes may be occurring in your body.
["D-dimer helps diagnose blood clots or bleeding disorders."]
Key facts at a glance
- LOINC
- 53148-3
- Short code
- dsDNA Ab Fld Ql
- Synonyms
- dsDNA Ab Fld Ql
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Is D-Dimer Used For?
D-dimer is primarily used to evaluate conditions involving blood clots, such as deep vein thrombosis (DVT) or pulmonary embolism. It can also support the diagnosis of other clotting disorders or help rule out bleeding complications in certain situations.
How Is the Test Performed?
A small blood sample is drawn from a vein, usually in your arm. The blood is processed to separate the serum or plasma, where the D-dimer levels are measured using an immunoassay method. This test is typically done quickly and can be part of a routine blood workup.
When Might You Need This Test?
Your healthcare provider may recommend a D-dimer test if you have symptoms like swelling, pain in your legs (possible DVT), chest pain or shortness of breath (possible pulmonary embolism), or if you have a history of clotting disorders. It may also be used in certain surgical or medical settings to monitor bleeding risks.
What Do My Results Mean?
High levels of D-dimer may suggest recent clot formation or clot-dissolving activity, while very low levels are usually normal. However, results alone cannot diagnose a clot or bleeding disorder without clinical correlation. Your doctor will interpret the results in the context of your symptoms and medical history.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
D-Dimer
Frequently asked questions
Why might my doctor order a D-dimer test if I don’t have symptoms?
Can D-dimer levels change over time, and how often should I get retested?
Is there anything I should do to prepare for this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy