Dual-Sample DNA Analysis for Antibody Screening and Confirmation (Fluid-Based)
This test checks for antibodies against DNA in your body fluids, often used to evaluate autoimmune conditions or immune system responses.
["Helps diagnose or monitor conditions linked to abnormal immune reactions to DNA."]
Key facts at a glance
- LOINC
- 109539-7
- Short code
- dsDNA Ab Msmt Fld
- Synonyms
- dsDNA Ab Msmt Fld
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms like joint pain, fatigue, or unexplained inflammation, or if you have a suspected autoimmune disorder. It may also be used in research or specialized diagnostic scenarios involving DNA-specific immune responses.
What to Expect Before the Test
No special preparation is typically needed. You may provide a sample of bodily fluid (like serum or plasma) depending on the clinical context. Follow your provider’s instructions for sample collection.
What the Test Results Mean
Results indicate whether antibodies against DNA are present. Positive findings may suggest conditions like systemic lupus erythematosus (SLE) or other autoimmune diseases. Results are interpreted by your healthcare provider based on your symptoms and medical history.
Common Conditions Monitored
This test is often used to diagnose or monitor autoimmune diseases where DNA antibodies play a role, such as lupus or other connective tissue disorders. It may also be part of broader diagnostic workups for unexplained immune system activity.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
DNA Antibody Test (Screen & Confirm)
Frequently asked questions
What causes my body to produce DNA antibodies?
Frequency depends on your condition and treatment plan. Some patients may need retesting every few months or annually to monitor disease activity or treatment effectiveness. Always follow your healthcare provider’s recommendations.
Most medications can be taken as usual unless your provider advises otherwise. Some medications (like steroids) may affect immune responses and could influence test results. Always inform your provider about all medications you’re taking.
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy