DNA Adherence or Binding Antibody Screen (Serum)
This test measures antibodies that may bind to DNA, sometimes linked to autoimmune conditions or certain inflammatory responses. Results help assess potential immune system activity.
["This screening helps identify possible autoimmune or inflammatory conditions by detecting antibodies targeting DNA."]
Key facts at a glance
- LOINC
- 5131-8
- Short code
- dsDNA Ab Ser Ql IF
- Synonyms
- dsDNA Ab Ser Ql IF
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- if
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test detects the presence of antibodies that can bind to deoxyribonucleic acid (DNA). These antibodies may be part of an immune response, sometimes seen in autoimmune diseases or other inflammatory processes. The method used is an immunoassay, which identifies specific proteins in your blood.
Why It’s Done
Your healthcare provider may order this test if you have symptoms like joint pain, fatigue, or unexplained fevers, or if you have a history of autoimmune diseases. It can also be part of a broader evaluation for conditions like lupus, rheumatoid arthritis, or other connective tissue disorders.
How It’s Performed
A blood sample is drawn from a vein, usually in your arm. The sample is then processed and tested in a lab to detect the presence of DNA-binding antibodies. Results are qualitative, meaning they indicate whether antibodies are present or not.
What the Results Mean
A positive result suggests the presence of DNA-binding antibodies, which may indicate an autoimmune or inflammatory condition. However, a single positive test does not confirm a diagnosis. Further testing and clinical correlation are needed.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
DNA-binding antibodies can be associated with autoimmune diseases such as systemic lupus erythematosus (SLE) or other connective tissue disorders. They may also appear in conditions involving chronic inflammation or immune activation. While not definitive, these findings prompt further evaluation to rule out or confirm underlying conditions.
Short name
DNA Antibody Screen
Frequently asked questions
Why might I need this test?
What does a positive result mean?
How long does it take to get results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy