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D-dimer (serum/plasma, quantitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of D-dimer, a breakdown product of clotting factors that forms when blood clots dissolve. It helps assess whether you’re at risk of blood clots or clot-related complications.

Quick summary

["D-dimer helps identify potential blood clotting risks or clot removal processes in your body."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
63225-7
Short code
dsDNA IgG Fld Ql IF
Synonyms
dsDNA IgG Fld Ql IF
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Doctors may order a D-dimer test to evaluate symptoms like unexplained shortness of breath, chest pain, leg swelling, or unexplained bruising. It’s also used to diagnose conditions like deep vein thrombosis (blood clots in veins) or pulmonary embolism (clots in the lungs).

What to Expect Before the Test

You’ll typically have a small needle inserted into your arm or hand to draw blood. The test is quick and usually done in a lab setting. Avoid strenuous activity or eating heavy meals 24 hours before the test if instructed by your provider.

What the Results Mean

High levels of D-dimer may suggest recent clot formation or conditions like deep vein thrombosis, pulmonary embolism, or certain cancers. Low or normal levels usually mean no significant clotting activity. Your doctor will interpret results in the context of your symptoms and medical history.

Common Conditions Monitored

This test is often used alongside other tests to diagnose or rule out blood clots, inflammation, or other clotting disorders. It can also help monitor conditions like disseminated intravascular coagulation (DIC), where the body forms clots in small blood vessels throughout the body.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: D-dimer plays a critical role in diagnosing and managing blood clotting disorders. Elevated levels often indicate active clot formation, guiding treatment decisions such as anticoagulant therapy. However, false positives can occur in conditions like pregnancy, cancer, or severe infections, so results should always be reviewed by a healthcare provider.

Short name

D-Dimer

Frequently asked questions

What causes a high D-dimer level?
High D-dimer levels can be caused by recent blood clots, surgeries, pregnancy, severe infections, or certain cancers. Your doctor will consider your symptoms, medical history, and other test results to determine the cause.
Can I eat or drink before this test?
You may eat and drink normally unless your doctor specifies otherwise. Some tests require fasting, but D-dimer tests do not. Always follow your healthcare provider’s instructions.
How long does it take to get results?
Results are usually available within a few hours to a couple of days, depending on your lab’s processing time. Your doctor will contact you once the results are ready, often within 24–48 hours.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy