DNA Immunoglobulin G (IgG) Free Light Chains (Serum)
This test measures the free light chains of Immunoglobulin G (IgG), a type of antibody protein in your blood. These light chains can sometimes appear in excess, which may indicate conditions like multiple myeloma or other immune system disorders.
["Measuring free light chains helps doctors diagnose and monitor certain blood disorders."]
Key facts at a glance
- LOINC
- 110951-1
- Short code
- dsDNA IgG Msmt Fld
- Synonyms
- dsDNA IgG Msmt Fld
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms like unexplained fatigue, frequent infections, bone pain, or if they suspect conditions such as multiple myeloma, lymphoma, or other immune-related diseases. It may also be used to monitor treatment progress or check for abnormal protein levels in your blood.
What to Expect Before the Test
No special preparation is needed for this test. You may have a small needle inserted into a vein in your arm to draw blood. It usually takes a few minutes, and you may feel a brief pinch. If you have a hard time with needles, let your provider know so they can help make it more comfortable.
What the Test Results Mean
The test measures the amount of free light chains in your serum. High levels may suggest conditions like multiple myeloma or other disorders affecting antibody production. Your results will be compared to a reference range provided by your healthcare provider, who will interpret them in the context of your overall health and symptoms.
Common Conditions Monitored
This test is often used to diagnose or monitor conditions such as multiple myeloma, where abnormal plasma cells produce too many light chains. It can also help detect other conditions like Waldenström macroglobulinemia or other lymphoproliferative disorders.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
IgG Free Light Chains
Frequently asked questions
What Does an Abnormal Result Mean?
Can Diet or Lifestyle Affect This Test?
How Often Will I Need This Test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy