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D-dimer (Serum/Plasma) Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of D-dimer, a protein fragment produced when blood clots break down. It helps assess whether you’re at risk of blood clots.

Quick summary

["D-dimer helps identify potential blood clotting issues, often used alongside other tests for conditions like deep vein thrombosis or pulmonary embolism."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
68956-2
Short code
dsDNA IgG Pcar IA-aCnc
Synonyms
dsDNA IgG Pcar IA-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is D-dimer Used For?

D-dimer is primarily used to evaluate blood clotting activity. A high level may suggest recent clot formation, while a low level may indicate no active clotting process. It’s often ordered alongside imaging tests to support a diagnosis of conditions like deep vein thrombosis (DVT) or pulmonary embolism (PE).

How Is This Test Performed?

Blood is drawn from a vein in your arm, and the serum or plasma sample is sent to a lab for analysis. The test measures the mass concentration of D-dimer using a specialized laboratory technique, often a turbidimetric or nephelometric assay.

Why Might Your Doctor Order This Test?

Your doctor may recommend a D-dimer test if you have symptoms like swelling, pain in the legs, shortness of breath, or a history of blood clots. It can also be used in certain screening or monitoring situations, such as before surgery or in patients with suspected clotting disorders.

What Are Common Results and Next Steps?

Results are not typically provided as absolute numbers but are interpreted in the context of your symptoms and medical history. High levels may prompt further testing (like imaging) to confirm a clot, while low levels may suggest no clot activity. Follow-up care depends on your doctor’s findings and recommendations.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: D-dimer in Diagnosis and Monitoring

Short name

D-dimer

Frequently asked questions

What does a high D-dimer level mean?
A high D-dimer level often indicates recent clot formation, which can help guide further testing or treatment for conditions like DVT or PE. However, it can also be elevated in other conditions, such as heart failure or infection, so results must be reviewed by a healthcare provider.
Can D-dimer levels be affected by other factors?
Yes, D-dimer levels can be influenced by factors like pregnancy, recent surgery, or certain medications (e.g., anticoagulants). Your doctor will consider these factors when interpreting your results.
How often should I get this test?
The frequency of this test depends on your medical condition and treatment plan. Your doctor will determine if repeat testing is needed based on your symptoms, response to treatment, or other clinical factors.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy