Skip to content

D-dimer, serum/plasma mass concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of D-dimer, a breakdown product of blood clots, to help assess whether clotting has occurred in your body.

Quick summary

["D-dimer helps identify potential blood clot risks or recent clotting events."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
33800-4
Short code
dsDNA IgG Ser-aCnc
Synonyms
dsDNA IgG Ser-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is D-Dimer Used For?

D-dimer is primarily used to evaluate conditions involving abnormal blood clotting, such as deep vein thrombosis (DVT) or pulmonary embolism. It can also support diagnosis of other clotting disorders or help rule out clotting-related complications after surgery or trauma.

How Is the Test Performed?

A blood sample is taken from a vein, usually in your arm. The blood is then processed to separate the plasma (liquid part) from cells. The D-dimer level is measured using a sensitive laboratory technique to detect its presence.

Why Might You Need This Test?

Your healthcare provider may order a D-dimer test if you have symptoms like swelling, pain in the legs (possible DVT), chest pain or shortness of breath (possible pulmonary embolism), or if you’ve had recent surgery, pregnancy, or conditions increasing clot risk.

What Do Results Mean?

High D-dimer levels may suggest recent clotting, while very low levels (often normal) help confirm no clotting is present. Results alone aren’t diagnostic—they’re usually interpreted alongside other tests and symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

D-Dimer

Frequently asked questions

How often will I need this test?
The frequency depends on your symptoms, medical history, and treatment plan. Your doctor will determine if repeat testing is needed, especially if you’re being monitored for clotting risks or managing conditions like cancer or heart disease.
What are the possible side effects of this blood draw?
Most people experience only mild discomfort or bruising at the injection site. Rarely, there may be slight swelling or bleeding, but these usually resolve quickly. If you have a bleeding disorder or take blood thinners, let your doctor know before testing.
Can I eat or drink before this test?
You can eat and drink normally unless instructed otherwise by your doctor. Some tests may require fasting, but D-dimer does not.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy