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Serum Immunoglobulin G (IgG) Level

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin G (IgG) in your blood, a type of antibody that helps fight infections and supports immune function.

Quick summary

["IgG helps protect your body against diseases and supports long-term immunity."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
63379-2
Short code
dsDNA IgG Ser Ql
Synonyms
dsDNA IgG Ser Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test to evaluate your immune system, check for infections, assess immune deficiencies, or monitor conditions like autoimmune diseases, chronic infections, or certain cancers. It can also help diagnose or monitor diseases such as HIV, hepatitis, or other immune-related disorders.

What to Expect Before the Test

No special preparation is usually needed. You may have a small needle inserted into your arm or vein to draw blood. If you’re on blood thinners, let your provider know before the test.

What the Results Mean

Results can vary based on your health, age, and other factors. Low IgG levels may suggest an immune system issue, while very high levels could indicate certain infections, inflammation, or autoimmune conditions. Your provider will interpret results in the context of your overall health.

Common Conditions Monitored

IgG levels are often checked in people with suspected immune disorders, chronic illnesses, or those who have had organ transplants to ensure their immune system is functioning properly.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

IgG is the most abundant antibody in your blood and plays a critical role in defending against bacteria and viruses. Low IgG levels may indicate a weakened immune response, increasing susceptibility to infections. High IgG levels can sometimes signal chronic inflammation, immune system activation, or certain medical conditions like multiple myeloma or severe infections.

Short name

IgG Level

Frequently asked questions

When Might I Need This Test?
You may need this test if you have symptoms like frequent infections, fatigue, unexplained weight loss, or if your doctor suspects an immune disorder, such as HIV, lupus, or a primary immunodeficiency.
What Are Normal IgG Levels?
There are no strict ‘normal’ ranges provided here since they vary by lab and individual factors. Your provider will compare your results to your baseline and overall health status.
Can Diet or Supplements Affect IgG Levels?
Dietary factors like protein intake may indirectly support immune function, but IgG levels are primarily influenced by your immune system’s response. Supplements like vitamins or herbs may not directly alter IgG levels but can support overall health.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy