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D-dimer, plasma (quantitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of D-dimer, a breakdown product of blood clots, to help assess whether clotting has occurred in your body.

Quick summary

["D-dimer helps identify potential blood clot risks or recent clotting events."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
63232-3
Short code
dsDNA IgM Fld Ql IF
Synonyms
dsDNA IgM Fld Ql IF
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is D-Dimer Used For?

D-dimer is primarily used to evaluate conditions involving blood clots, such as deep vein thrombosis (DVT) or pulmonary embolism. It can also support the diagnosis of other clotting disorders or help rule out certain bleeding risks in some cases.

How Is the Test Performed?

A blood sample is taken from a vein, usually in your arm. The blood is processed to separate plasma, where the D-dimer levels are measured using a sensitive immunoassay technique. This test does not require fasting.

Why Might You Need This Test?

Your healthcare provider may order a D-dimer test if you have symptoms like leg swelling, chest pain, shortness of breath, or if you’ve been diagnosed with a condition that increases your risk of blood clots, such as recent surgery, pregnancy, or long periods of inactivity.

What Are Possible Results?

Results are interpreted based on your clinical situation. High levels of D-dimer often suggest recent clot formation, while very low levels may indicate no active clotting. Your doctor will discuss the meaning of your specific result in relation to your symptoms and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

D-Dimer

Frequently asked questions

How Often Does This Test Cause Side Effects?
Most people experience only mild discomfort or bruising at the injection site from the blood draw. Rarely, there may be slight swelling or redness, but these are usually temporary. If you experience severe pain or signs of infection (like fever or increased redness), contact your healthcare provider.
What Should I Do Before the Test?
No special preparation is needed for this test. However, inform your healthcare provider about any medications you’re taking, especially blood thinners, as they may affect results. Avoid heavy exercise or strenuous activity before the blood draw.
Can I Drink Alcohol Before the Test?
Alcohol consumption in moderation is generally fine before this test, but avoid excessive amounts. If you’re unsure, ask your healthcare provider for personalized advice.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy