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Serum Creatinine (Creatinine Level)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood. It helps assess how well your kidneys are filtering blood.

Quick summary

["Your kidneys filter waste from your blood, and creatinine is one key marker of kidney function."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
72281-9
Short code
Ds INR range/Ds INR det Patient-Rto
Synonyms
Ds INR range/Ds INR det Patient-Rto
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Doctors may order this test to check for kidney problems, monitor kidney disease progression, or evaluate how well your kidneys are working after treatment for conditions like high blood pressure or diabetes.

What Does a Result Mean?

Higher than expected levels may suggest kidney damage or disease, while lower levels could indicate dehydration or muscle loss. Your doctor will interpret results in the context of your overall health.

How Is the Test Performed?

A blood sample is taken from a vein, usually in your arm. The sample is sent to a lab where it is analyzed to measure creatinine levels.

What Can Affect Results?

Factors like dehydration, recent exercise, or certain medications can temporarily change creatinine levels. Also, conditions like muscle disorders or liver disease may influence results.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: serum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is crucial for diagnosing and managing kidney-related conditions. Elevated creatinine levels often indicate impaired kidney function, prompting further evaluation or treatment adjustments. It’s also used to monitor chronic kidney disease, assess kidney function before surgeries, or evaluate response to treatments for conditions affecting the kidneys.

Short name

Creatinine

Frequently asked questions

Why might my creatinine level be higher than expected?
Possible reasons include kidney disease, dehydration, high muscle mass, heart failure, or certain medications. Your doctor will discuss your results with you and may recommend follow-up tests.
Could my diet affect my creatinine levels?
Dietary changes like eating more protein or certain supplements can temporarily influence creatinine levels. However, your doctor will consider your overall health and medical history when interpreting results.
What if my creatinine level is very low?
Very low levels may suggest dehydration, muscle loss, or conditions like liver disease. Your doctor will review your results alongside other health factors to determine the cause and next steps.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy