Skip to content

Prescription Opioid Use and Health Consequences — Past 3 Months

Published: August 9, 2026Updated: August 16, 2026

A questionnaire assessing how often prescription opioid use has caused health problems during the previous 3 months.

Quick summary

This screening question helps identify possible opioid-related harm and whether medication use should be reviewed with a clinician.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
95458-6
Short code
DURINGTHEPAST3MOHOWOFTENHASYOURUSEOFPRESCRIPTIONOPIOIDSLEDTOHEALTH
Synonyms
—
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
7
Ref high
56
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
nida
CPT
84484
SNOMED
302773008
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This is a patient-reported screening questionnaire, not a blood or laboratory test. It asks how often your use of prescription opioids has led to health problems during the past 3 months.

Why might I need this test?

Clinicians may use it to screen for opioid-related adverse effects, problematic use, or an need to reassess pain treatment. It can also help guide safer prescribing and pain-management discussions.

How is the test performed?

You answer the question based on your experiences during the previous 3 months. Your response is recorded as part of a questionnaire and interpreted along with your medical history, medications, symptoms, and clinical evaluation.

How do I prepare for the test?

No special preparation is needed. Think about whether prescription opioid use has caused symptoms such as excessive sleepiness, constipation, nausea, impaired coordination, confusion, or other health problems during the past 3 months.

Reference range

Adult males: 7-56 U/L; Adult females: 7-43 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Reporting that prescription opioid use often or very often led to health problems may indicate adverse medication effects, impaired functioning, misuse, or difficulty managing pain. This result does not by itself establish opioid use disorder or another specific diagnosis. A clinician may review your medications, dosage, other substances, and symptoms and may recommend treatment, monitoring, or changes in therapy.

Short name

Prescription Opioid Health Consequences

Frequently asked questions

Does this test measure opioids in my body?
No. It is a questionnaire about the frequency and impact of health problems associated with your prescription opioid use.
What should I consider when answering?
Consider physical effects, reduced alertness or functioning, digestive symptoms, falls, and any other health problem you believe was related to opioids during the past 3 months.
What if I am not sure whether my health problems were caused by opioids?
Give your best estimate and discuss the uncertainty with your clinician. Other medications and medical conditions may also contribute, so the questionnaire is usually interpreted as part of a broader assessment.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy